We Are Personalized Medicine.

Founded in 2009, and based in Southern California Proove Biosciences is a commercial and research leader in personalized medicine. Proove has a portfolio of patent-protected genetic tests that help physicians answer some of their most important concerns to improve care and reduce costs.

Since most patients go to the doctor for help with physical or emotional pain, Proove has laid a successful foundation as the leader in personalized pain medicine and has plans to expand into other specialties. With a high-complexity CLIA-certified laboratory in Irvine, California, the Company also has offices in the Baltimore-Washington area to support hundreds of treating physician offices and clinical research sites across the United States.


Our mission is to change the future of medicine.

We seek to realize a future when clinicians look back and wonder how they could’ve ever prescribed medications without knowing how a patient would respond.



Hi, my name is Carol and my husband was going in to have back surgery…

He was going to have the potential to have a lot of pain. Knowing my husbands’ opioid risk was a great concern of mine.

I had some concerns that he could possibly have the potential be addicted to painkillers. Getting clarity about the opioid risk potential set my mind at ease based on the score that came back from the Proove test. The test results from Proove showed that my husband should not take NSAID drugs, and in the past he had been taking those drugs.

Things are going to change because of these Proove tests.

Carol Yarbrough

Carol Yarbrough Wife of Mayor Jim Yarbrough

“My name is Jackie. I found out about Proove because my doctor needed to know more about why I had poor responses to common medicines…”

My doctor sent my DNA sample to Proove’s laboratory. The test results came back quickly and he was able to determine a safer course of treatment for me…

I’m very thankful for how Proove’s testing and genetic research helped me and I’m very impressed with the compassion of the founders and staff…

Proove is changing the future of medicine and most importantly, leading the way to better health for people like me…

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Jackie Putt

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